1,2,3,4-TETRAHYDRO-QUINOLINE-8-CARBOXYLIC ACID

1,2,3,4-TETRAHYDRO-QUINOLINE-8-CARBOXYLIC ACID - Names and Identifiers

Name	1,2,3,4-tetrahydroquinoline-8-carboxylic acid
Synonyms	Zinc03953327 AURORA KA-4612 AKOS A0602-0914 4-tetrahydro-8-Quinolinecarboxylic acid 1,2,3,4-TETRAHYDRO-8-QUINOLINECARBOXYLIC ACID 1,2,3,4-tetrahydroquinoline-8-carboxylic acid 1,2,3,4-tetrahydro-quinoline-8-carboxylic acid 1,2,3,4-TETRAHYDRO-QUINOLINE-8-CARBOXYLIC ACID 8-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro- 8-quinolinecarboxylic acid, 1,2,3,4-tetrahydro-
CAS	34849-19-9
InChI	InChI=1/C10H11NO2/c12-10(13)8-5-1-3-7-4-2-6-11-9(7)8/h1,3,5,11H,2,4,6H2,(H,12,13)

1,2,3,4-TETRAHYDRO-QUINOLINE-8-CARBOXYLIC ACID - Physico-chemical Properties

Molecular Formula	C10H11NO2
Molar Mass	177.2
Density	1.223±0.06 g/cm3(Predicted)
Melting Point	162 °C(Solv: water (7732-18-5); ethanol (64-17-5); cyclohexane (110-82-7))
Boling Point	371.0±31.0 °C(Predicted)
Flash Point	178.2°C
Vapor Presure	3.67E-06mmHg at 25°C
pKa	2.84±0.20(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.587

1,2,3,4-TETRAHYDRO-QUINOLINE-8-CARBOXYLIC ACID - Risk and Safety

Hazard Class

IRRITANT

1,2,3,4-TETRAHYDRO-QUINOLINE-8-CARBOXYLIC ACID - Introduction

1,2, 3,4-tetrahydro-8-quinolinecarboxylic acid is an organic compound with the chemical formula C10H13NO2. The following is its nature, use, preparation and safety information:

Nature:
1,2, 3,4-tetrahydro-8-quinolinecarboxylic acid is a white crystalline solid. It is stable at room temperature and soluble in organic solvents such as chloroform, benzene and ethanol. It has a molecular weight of 191.22g/mol and is pharmaceutically active.

Use:
1,2, 3,4-tetrahydro-8-quinolinecarboxylic acid is widely used in the field of medicine. It can be used as an intermediate for the synthesis of drugs and for the preparation of the skeleton of various drug molecules. In addition, it can also be used in organic synthesis reactions, such as the synthesis of nitrogen heterocyclic compounds.

Preparation Method:
The preparation of 1,2, 3,4-tetrahydro-8-quinolinecarboxylic acid is usually carried out by reacting 8-carbonylquinoline and a reducing agent (such as zinc) under acidic conditions. The reduction product produced by this reaction is subjected to acid treatment to obtain the target product.

Safety Information:
1,2, 3,4-tetrahydro-8-quinolinecarboxylic acid has certain safety under proper operation. However, it is an organic substance and may be somewhat toxic and irritant. Therefore, appropriate protective measures, such as gloves, glasses and protective clothing, should be taken when using, handling or coming into contact with the compound. Also, be sure to operate in a well-ventilated area and store and handle the compound properly. It is best to consult the safety data sheets and the relevant chemical literature for more detailed safety information on a case-by-case basis.

Last Update：2024-04-09 21:32:40